A framework to guide selection of chemical alternatives by National Research Council, Division on Earth and Life

By National Research Council, Division on Earth and Life Studies, Board on Environmental Studies and Toxicology, Board on Chemical Sciences and Technology, Committee on the Design and Evaluation of Safer Chemical Substitutions: A Framework to Inform Governme

Traditionally, laws governing chemical use have usually all in favour of primary chemical compounds and acute human well-being results of publicity to them, in addition to their capability to reason melanoma and different adversarial health and wellbeing results. As medical wisdom has extended there was an elevated know-how of the mechanisms in which chemical substances might exert damaging results on human health and wellbeing, in addition to their results on other  Read more...

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Extra info for A framework to guide selection of chemical alternatives

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A more complete discussion of the planning activities associated with this step can be found in Chapter 4. Likewise, promising alternatives should not be disqualified because of data gaps that could be filled later. Alternatives eliminated from consideration at this step should be documented both for transparency purposes and in case it is determined that they should be re-examined at later stages of the assessment. Chapter 4 includes a more complete discussion on identifying and screening potential alternatives.

Defining those elements provide a baseline for comparisons of potential alternatives. Clearly articulating the negative effects of the original substance also helps in establishing human health and ecological goals for the alternatives. A more complete discussion of the information that should be gathered in this step, and the benefits of doing so can be found in Chapter 4. 28 A Framework to Guide Selection of Chemical Alternatives Formal assessment planning is included in four frameworks (IC2, CA SCP, Lowell, and UCLA MCDA) and has been included in the committee’s framework.

In fact, one framework (UCLA MCDA) is a tailored form of decision analysis, which is a logical procedure for balancing factors from different domains to make decisions (Belton and Stewart 2002).

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