Advances in bacterial pathogen biology by Robert K. Poole

By Robert K. Poole

This quantity is an updated evaluate of the body structure of chosen pathogenic micro organism. each one bankruptcy is written by means of specialists within the box of that organism.The concentration is on biochemistry and body structure yet issues of scientific relevance are included.

Key features:

  • Contributions from top specialists
  • Informs and updates on the entire most up-to-date advancements within the box

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Read, R. , & Moir, J. W. (2002). Nitric oxide metabolism in Neisseria meningitidis. Journal of Bacteriology, 184, 2987–2993. Arai, H. (2011). Regulation and function of versatile aerobic and anaerobic respiratory metabolism in Pseudomonas aeruginosa. Frontiers in Microbiology, 2, 103. , & Igarashi, Y. (1997). Cascade regulation of the two CRP/FNRrelated transcriptional regulators (ANR and DNR) and the denitrification enzymes in Pseudomonas aeruginosa. Molecular Microbiology, 25, 1141–1148. , Hade, M.

2003). Characterization of the roles of NikR, a nickel-responsive pleiotropic autoregulator of Helicobacter pylori. Molecular Microbiology, 49, 947–963. Energetics of Pathogenic Bacteria 47 Cook, G. , & Berney, M. (2014). Energetics of respiration and oxidative phosphorylation in mycobacteria. In G. Hatfull, & W. R. Jacobs, Jr. ), Molecular genetics of mycobacteria. Washington, DC: ASM Press. Cotter, P. , Gennis, R. , & Gunsalus, R. P. (1990). Cytochrome o (cyoABCDE) and d (cydAB) oxidase gene expression in Escherichia coli is regulated by oxygen, pH, and the fnr gene product.

Nucleatum, another smf-based pathogen, conserves free energy by fermenting amino acids such as glutamate via the glutaconyl-CoA pathway (Bakken, Hogh, & Jensen, 1989; Beatrix, Bendrat, Rospert, & Buckel, 1990). Through landmark studies of this pathway in fusobacteria and clostridia, Buckel has concluded that energy generation depends on the concurrent processes of decarboxylative phosphorylation and electron bifurcation. , 1990). It is proposed that the high0 potential crotonoyl-CoA (E0 ¼ À10 mV) and low-potential ferredoxin 0 (E0 ¼ À400 mV) are thereafter simultaneously reduced by electrons derived 0 from the mid-potential NADH (E0 ¼ À280 mV); this electron bifurcation is mediated by the multimeric complex Bcd/EcfBC and depends on flavin serving as a two-electron gate.

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