Advances in Parasitology, Vol. 48 by John R. Baker, Ralph Muller, David Rollinson

By John R. Baker, Ralph Muller, David Rollinson

Advances in Parasitology is a sequence of in-depth stories on present issues of curiosity in modern parasitology. It contains scientific reviews on parasites of significant effect, similar to trypanosomiasis and scabies, and extra conventional parts, akin to zoology, taxonomy, and lifestyles heritage, which form present considering and functions.

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R. A. J. SCHOFIELDAND W. 3. ssu rRNA Phylogenies Phylogenies of the genus Leishmania based on gene sequencing, with resolution suitable for the classification of the Leishmania species complexes, took a relatively long time to appear. In general, the most widely used genes in molecular phylogenies are the ssu rRNA gene and mitochondrial gene sequences. , 1994) means that considerable caution must be exercised when using these genes for phylogenetic analysis. Large numbers of partial sequences of the ssu rRNA gene were collected by van-Eys et al.

This led the authors to propose that the Leishmania/Endotrypanum clade had evolved from monogenetic parasites of sandflies in the New World during the early Cenozoic and had migrated to the Old World no later than the mid-Miocene. It was suggested that the reptilian Leishmania species had evolved in the Old World from these immigrant mammalian parasites. Since it had been impossible to distinguish between the Leishmania complexes on the basis of the sequence of the ssu rRNA gene, it was surprising that RFLP-based classification could give a reliable result.

Cruzi 2, we propose that divergence to T. R. A. J. SCHOFIELDAND W. GIBSON rodent hosts. Of particular interest is the possible fate of clonet 39 (Tibayrenc and Ayala, 1988), which is strongly associated with caviid rodents in Bolivia, with Triatoma infestans and with virulent human infections throughout much of the 'southern cone' region of South America. , 1998), strongly suggests that T. infestans originated in the Cochabamba/Sucre region of central Bolivia, from where it has been spread in association with human migrations, mainly over the last 100-150 years.

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