By A. Misra
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Iii. The biventricular heart failure models, often called for testing of cardiac assist devices, which remain difficult to achieve in animals. The most part of these mechanical assists devices are usually tested in computational version (Querzoli, 2011) or WindKessel models, away from the pathophysiological aspect in humans (Olufsen & Nadim A, 2004). g. malignancy); coronary atherosclerosis, follow up costs and surgical complications, all contribute to limiting the generalization of such treatments in practice.
A symbolic example observed in athletics, high physical performance, which means shear stress-mediated endothelial function, could be achieved with slow heartbeat (shear rate) and increased stroke volume (pulse pressure). In contrast, in any abnormal hemorheological state, microcirculation presents behavior that approaches that of Bernoulli’s law, as interpreted by the FahraeusLindqvist effect in which plasma stuck at the inner vascular boundary layers while erythrocytes move faster at the center (Fahraeus & Lindqvist, 1931; Neri Serneri, 1981).
Corresponding to adult heart patients. In addition CAD are generally first designed for management adult heart diseases and then miniaturized to cope with pediatric populations. However; pediatric patients are more vulnerable to hemodynamic disturbances caused by right heart failure due to congenital anomalies and they are vulnerable to vascular complications caused by small vessels geometries in content (Potapov, et al 2007). Adults usually suffer from ischemic left ventricular heart diseases with atherosclerotic vessels and they are therefore more vulnerable to vascular complications (Nour S, 2008).