Chamomile : industrial profiles by Rolf Franke, Heinz Schilcher

By Rolf Franke, Heinz Schilcher

For over 2000 years, arrangements of chamomile plants have counted one of the medicinal treasures of many cultural teams. This booklet offers an interdisciplinary stock of the medical point of data approximately German chamomile in addition to Roman chamomile, the 2 kinds of chamomile so much produced. It comprises info for pharmacists and the pharmaceutical approximately chamomile arrangements and crucial chamomile oil. Physicians and toxicologists will locate unique descriptions of the most recent experimental stories and using chamomile arrangements in conventional and healing makes use of. additionally it is the most recent info of use to growers and pharmaceutical marketers

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49, 67–73. 72. , Kunde, R. (1979) Pharmacological investigations with compounds of chamomile. II. New investigations on the antiphlogistic effects of (–)α -bisabolol and bisabolol oxides. , 35, 125–140. 73. -J. (1991) in T. Nasemann, R. ) Kamillosan® im Spiegel der Literatur. Frankfurt, Germany: pmi Verlag, 85–86. 74. Katz, R. (1928) Fortschr. , 46, 388–391. 75. J. (1992) in O. C. I. ) Liposome Dermatics, Berlin: Springer-Verlag, 329–337. 76. , Schmid, M. (1993) Eur. J. Clin. , 44, 315–318. 77.

1996) Z. , 71, 542–546. 71. , Flaskamp, E. (1983) Pharmakologische Untersuchungen von Kamilleninhaltsstoffen. VI. Untersuchungen zur antiphlogistischen Wirkung von Chamazulen und Matricin. , 49, 67–73. 72. , Kunde, R. (1979) Pharmacological investigations with compounds of chamomile. II. New investigations on the antiphlogistic effects of (–)α -bisabolol and bisabolol oxides. , 35, 125–140. 73. -J. (1991) in T. Nasemann, R. ) Kamillosan® im Spiegel der Literatur. Frankfurt, Germany: pmi Verlag, 85–86.

In a 48-h patch test in volunteers, matricaria oil neither caused skin irritation nor were there any discernible sensitization reactions or phototoxic effects. Matricaria oil was granted “generally recognized as safe” (GRAS) status by FEMA and has been approved by the FDA for use in food and cosmetics [88]. The acute oral toxicity of (−)-α-bisabolol in mice and rats was very low with an LD50 of about 15 ml/kg. A 6-week subacute toxicity study showed that the lowest toxic oral dose of (−)-α-bisabolol in rats and dogs was between 1 and 2 ml/kg.

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