Human Developmental Toxicants: Aspects of Toxicology and by James L. Schardein (Author), Orest T. Macina (Author)

By James L. Schardein (Author), Orest T. Macina (Author)

Providing the 1st database of its variety, this specified reference illustrates the relationships among the chemistry and developmental toxicity of a couple of very important prescribed drugs and commercial toxicants. Human Developmental Toxicants includes up to date and concise info at the chemical buildings, houses, and organic actions for fifty identified brokers that adversely have an effect on prenatal and postnatal human improvement by way of progress, viability, constitution, and serve as. This publication offers information linking chemical and structural houses of particular toxicants as they relate to poisonous results, dosage, timing, and direction of publicity. targeting one compound in step with bankruptcy, the publication additionally comprises linked organic information from animals for every agent coated. An accompanying CD summarizes all the information mentioned within the textual content inside an digital database. furthermore, the CD comprises third-dimensional constitution representations and forty nine calculated physicochemical and topological parameters of the chosen molecules. this data turns out to be useful for construction constitution job dating (SAR) versions linking the chemical houses with saw human developmental toxicity. As scientists proceed to discover how chemical substances adjust human improvement, Human Developmental Toxicants comprises the mandatory details to extra establish which chemical houses are accountable for antagonistic results. This reference offers toxicologists, teratologists, chemists and different scientists with the newest info and data had to practice possibility checks, are expecting chemical compounds which may produce developmental toxicity, and keep watch over destructive publicity.

Show description

Read Online or Download Human Developmental Toxicants: Aspects of Toxicology and Chemistry PDF

Best toxicology books

Benzene - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References

This can be a 3-in-1 reference publication. It offers an entire scientific dictionary overlaying enormous quantities of phrases and expressions when it comes to benzene. It additionally provides large lists of bibliographic citations. eventually, it presents info to clients on the best way to replace their wisdom utilizing a number of web assets.

Botulinum Toxins in Clinical Aesthetic Practice, Second Edition

Good illustrated with high quality photos, Botulinum pollution in medical Aesthetic perform has confirmed itself a greatest advisor to the medical use of alternative kinds of botulinum pollution for either esthetic and scientific reasons. This moment variation keeps all of the beneficial properties that made its predecessor such a success, together with certain anatomic drawings, a overview of different formulations to be had, and specimen varieties.

Advances in Microbial Food Safety: Volume 2

Learn and laws in meals microbiology proceed to adapt, and outbreaks of foodborne affliction position extra strain at the to supply microbiologically secure items. This moment quantity within the sequence Advances in Microbial nutrients protection summarises significant contemporary advances during this box, and enhances quantity 1 to supply a vital review of advancements in meals microbiology.

Biological and chemical terrorism: a guide for healthcare providers and first responders

Might you know the symptoms of a organic or chemical weapon assault? may you understand how to diagnose and deal with your sufferers? could you know the way to guard your employees and your self in doing so? For solutions to questions like those in an issue of mins, flip to this e-book: the 1st particularly designed to guide you thru id of the main most likely organic or chemical guns utilized in a bioterrorist assault.

Extra info for Human Developmental Toxicants: Aspects of Toxicology and Chemistry

Sample text

1990). Pregnancy after chemotherapy for gestational trophoblastic disease. J. Reprod. Med. 35: 522–524. Bawle, E. , Conard, J. , and Weiss, L. (1998). Adult and two children with fetal methotrexate syndrome. Teratology 57: 51–55. Buckley, L. M. et al. (1997). Multiple congenital anomalies associated with weekly low dose methotrexate treatment of the mother. Arthritis Rheu. 40: 971–973. Christophidis, N. (1984). Methotrexate. Clin. Rheum. Dis. 10: 401–415. delCampo, M. et al. (1999). Developmental delay in fetal aminopterin/methotrexate syndrome.

L. , Crickmay, G. , and Vaughan Jones, R. (1968). Pregnancy in a case of chronic lymphatic leukemia. Br. J. Obstet. Gynaecol. 75: 1165–1168. Didcock, K. , and Robson, J. M. (1956). The action of some nucleotoxic substances in pregnancy. Br. J. Pharmacol. 11: 437–441. Jacobs, C. et al. (1981). Management of the pregnant patient with Hodgkin’s disease. Ann. Intern. Med. 95: 669–675. Lacy, C. F. et al. (2004). Drug Information Handbook (Pocket), 2004–2005, Lexi-Comp. , Hudson, OH. Monie, I. W. (1961).

1964). Production of ovarian dysgenesis in the rat and human by busulfan. Am. J. Obstet. Gynecol. 89: 414–420. Lacy, C. F. et al. (2004). Drug Information Handbook (Pocket), 2004–2005, Lexi-Comp. , Hudson, OH. Malakhovsky, V. G. (1969). Behavioral disturbances in rats receiving teratogenic agents antenatally. Biull. Eksp. Biol. Med. 68: 1230–1232. Moloney, W. C. (1964). Management of leukemia in pregnancy. Ann. NY Acad. Sci. 114: 857–867. Nicholson, H. O. (1968). Cytotoxic drugs in pregnancy. Review of reported cases.

Download PDF sample

Rated 4.21 of 5 – based on 28 votes